Any packet can be sent on a new socket provided the supplied destination information is correct. To send on a new socket make sure the "On New Connection" button is checked in the "Send" group:
The field above the Actions group will display whether or not the operation succeeded. Additionally the field next to it may give a more specific error message:
By default Packet Edit Studio saves connection information about every packet so that if you bring it up later the default remote address will be the same as the original address. You can view the original packet path at the top of the dialog:
